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this difference may result from a ~5x stronger effect produced by GLP-1 analogs, compared to DPP-4 inhibitors (Charbonnel & Cariou, 2011) No change in weight Contraindications: type I diabetes (these patients lack pancreatic beta cells) diabetic ketoacidosis (it would not be effective for treating this condition) an association between DPP-4 inhibitors and heart failure has been observed for two members of this drug class in patients with type 2 DM and atherosclerosis

Better functional recovery: Beyond structural healing, the combination improves functional recovery the return of normal function and performance

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Endothelial glucocorticoid receptor is required for protection against sepsis

[10] These are the most speculative extensions of the systemic story: they rest on gene-signature matching and in-vitro observations, and they should be read as directions researchers find interesting rather than as demonstrated systemic effects