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Main Targets: Dark spots

40 It is FDA approved for the treatment of schizophrenia and bipolar I disorder and as an adjunctive treatment for major depressive disorder

Global normalization of reporter ion intensity values was performed relative to the overall abundance of total protein in each replicate, and the normalized values were log 2 transformed

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To gain a comprehensive understanding of the role of secondary BAs in MDD and the potential effects of antidepressant medications on the gut microbiota and BA synthesis, further research is necessary