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Omega-3 PUFAs originate from alpha-linolenic acid (ALA), while omega-6 PUFAs come from linoleic acid (LA)

doi: 10.1038/sj.ejcn.1602410

doi: 10.3389/fnagi.2022.804890 356 WaxmanS

COMT inhibitors (e.g., entacapone, tolcapone, opicapone) prolong levodopa's halflife by preventing its peripheral degradation, increasing its availability in the brain, and enhancing the duration of dopamine action [6]

Research should be committed to the development of combination therapies, integrating ferroptosis inducers with traditional chemotherapy, radiotherapy, targeted therapy, or immunotherapy to enhance therapeutic effects and reduce the resistance associated with monotherapy

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