ovarian cancer and glutathione Unbiased assessment of APR-246 responsive p53 mutants in Glutathione and Thioredoxin Antioxidant Pathways

Although their largest involvement is in nutrient and metabolic regulation, around 10% of them might cross the BBB, as shown in animal studies with mechanistic details (Monteiro-Cardoso et al., 2021)

There are two types of lupus mouth sores: The first type happens outside of flares as a side effect of many lupus medications

By 24h, microglia had removed all apoptotic debris with an effective clearance time of 41 min per apoptotic cell

The autophagy adaptor p62/SQSTM1, essential for targeting ubiquitinated substrates to autophagosomes, is mutated in ALS and FTD, where impaired p62 function results in aggregation-prone protein accumulation and neuronal toxicity

ERK1/2-activated de novo Mapkapk2 synthesis is essential for osteogenic growth peptide mitogenic signaling in osteoblastic cells

doi: 10.1152/physrev.00048.2019