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Opening a cold vial invites condensation from the air, and that moisture is a stability killer

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doi:10.1007/s12035-018-0933-z Mao L, Hochstetter D, Yao L, et al

doi: 10.1111/j.1447-0756.2012.01844.x

Either way, long story short, this spot, coincidentally is also where the dog had an embedded foxtail that had burrowed its way into the muscle

Duration of analgesic effect is usually 4 to 6 hours