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Anoxic depolarization, which occurs during ischemia, triggers ATP release from neurons and glial cells leading to a marked elevation of extracellular ATP concentration (Dale and Frenguelli, 2+ overload, tissue excitotoxicity, and amplification of the inflammation (Domercq et al., 2018)

There's one important safety consideration: people with G6PD deficiency (a genetic enzyme condition) should avoid glutathione therapy entirely, as it can cause serious complications

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Forty-eight-hour post transfection lentiviral supernatant was collected, filtered through 0.45 m filter and used directly or stored at 80 C