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Melatonin is present in high concentrations in the mitochondria, which can prevent the oxidation of cardiolipin and help to restore mitophagy in PD (Xiang et al., 2020

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FIGURE 7 Previous studies have shown that deferoxamine (DFO) inhibits the growth of esophageal squamous cell carcinoma (ESCC) cells by activating the ERK pathway in a ROS-dependent manner (Supplementary Figure S3E), and treatment with 800 M CGA led to a significant increase in ROS accumulation in hepatocytes (Figures 7F,G)

As the planet neared the intense gravitational influence of the white dwarf, parts of it may have been ripped away or the entire planet torn to shreds