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The cutoff value for significant BP, KEGG, and Wiki pathway results was an adjusted p -value 0.05

Based on the known role of insulin/IGF-I as inhibitors of Tau phosphorylation by inhibiting a major Tau kinase, such as glycogen synthase kinase-, numerous observations demonstrated that IGF-I controls the levels of hyperphosphorylated Tau in brain [326,327]

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Vitamin B6 and its role in cell metabolism and physiology