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Microplastics Exposure Causes the Senescence of Human Lung Epithelial Cells and Mouse Lungs by Inducing ROS Signaling

Science (journal) 298 (5601): 214953

These effects are established during developmental time slots when the system is primed for staged development during gestation and the perinatal period

Nat Commun 2019;10:3126

Acrolein is formed endogenously from polyamines by copper-dependent amine oxidases (plasma/serum amine oxidase, diamine oxidase, and semicarbazide-sensitive amine oxidase) and by FAD-dependent polyamine oxidases, monoamine oxidase, and spermine/polyamine oxidase [53]