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doi:10.4315/0362-028X.JFP-17-094

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Age: The effects of age on the pharmacokinetics of bupropion and its metabolites have not been fully characterized, but an exploration of steadystate bupropion concentrations from several depression efficacy trials involving subjects dosed in a range of 300 to 750 mg per day, on a 3-times-daily schedule, revealed no relationship between age (18 to 83 years) and plasma concentration of bupropion

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People should be aware there are still toxic substances in the iQOS." Auer and Glantz's concerns were echoed by several people who spoke during a public comment period on the second day of the hearing