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Loss-of-function mutations in GSNOR1 increased total cellular NO and SNO content and compromised both non-host and resistance ( R ) gene-mediated protection and also disabled basal defense responses (Wang et al., 2010

Their function is critically dependent on the mitochondrial DNA (mtDNA) genome, which encodes core subunits of the electron transport chain, as well as ribosomal and transfer RNAs

Prog Lipid Res (2005) 44:12553

To meet the diagnostic criteria for clEDS, a person must meet all three major criteria AND have a family history compatible with autosomal recessive inheritance

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Some clients see more dramatic changes than othersit really depends on your individual skin type and genetics