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Further investigation is needed to investigate whether spinal cord elements may also be involved

Additionally, research indicates upregulation of growth hormone receptor expression in tendon-derived fibroblasts, potentially amplifying growth hormonemediated proliferative responses during repair

The ability of glial cells to relay synaptogenic and axonal information to surrounding elements gives glia a characteristically neuronal character

The acute exposure of exogenous estradiol has also been reported to rescue the reduction in hippocampal proliferation following ovariectomy although these effects are highly dependent on dose, duration of hormone exposure and time of analysis post-surgery [141]