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The researchers commented that these might include important systems, namely, dopamine-, NO-, prostaglandin-, somatosensory neuron-system, and more

Biogerontology (NLM) .Read source (2006)

Hebert A, Thiboutot D, Stein Gold L, Cartwright M, Gerloni M, Fragasso E, Mazzetti A

Patients utilizing KPV will need to transition to other anti-inflammatory management strategies under the guidance of their medical team

(6) neurotrophic agents offer the ability to facilitate synaptogenesis, neurogenesis and neuroprotection thus greater research attention must be directed toward creating small molecule analogs designed to penetrate the BBB and activate these brain systems

Additionally, the procedure can be painful, deterring many from choosing this method