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P+C = Pemetrexed + platinum chemotherapy + placebo

Some compounds that protect hair cells from aminoglycoside exposure, for example tacrine and other quinoline ring-containing structures, do so by inhibiting aminoglycoside uptake (Ou et al., 2009, 2012)

Many authors recommend a minimum 3-month wash-out

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Because of this interest, a brain permeable and orally available p38MAPK inhibitor has recently been developed (MW150, a.k.a