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Therefore, low-dose chelation strategies are preferred to maintain neuroprotection without disrupting systemic iron balance

While there are different models to study glutathione metabolism, in this study we used BSO as it is a specific and potent chemical inhibitor of the rate limiting enzyme GCLC (38)

Chronic alcohol feeding combined with multiple high-dose alcohol gavages can simulate the drinking patterns of most patients with liver disease and are highly similar to the pathogenesis of human ALD

JP patent 52,156,994 Miyamoto T, Miwa N, Takemoto T (1978) Glutathione

Screening by determining total homocysteine (tHcy) in dried blood spots is only occasionally performed given the need for a reduction step prior to LC-MS/MS assay and associated costs [42]