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The vast majority of studies on the capacity of genetic vaccines to transfect muscle cells and to induce specific immune responses in vivo have employed a mouse model

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[27] Yago MR, Frymoyer AR, Smelick GS, et al

Jeschke MG, Herndon DN, Vita R, Traber DL, Jauch KW, Barrow RE

( A ) Cell-growth assay following FG4592 (100 M) and DMF cotreatment

(30) suggesting that insulin resistance and glucose toxicity within the CNS of patients with T2D damages axon integrity, inhibits nerve impulses, and degrades myelin in oligodendrocytes, leading to cognitive dysfunction