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5.9.4 Enzyme-linked immunospot Splenocytes were used in ELISpot assays to measure cytokine secretion upon metE stimulation

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Cel Biochem 112 (1), 107117

Wnek agrees, and explains that "because of how deep these fat cells lie, it may be hard for caffeine in topical products to reach the target site to work." "Some benefits may be immediate, resulting from a temporary vasoconstriction of blood vessels, such as what occurs with caffeine, in which case using a cream in the days prior to a vacation may provide some instant benefit," said Dr