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As well as being a precursor to several diseases, oxidative stress is also believed to cause inflammation and contribute to visible aging

Besides genetic alterations, epigenetic mechanisms have recently emerged as key regulators of gene expression inducing transcription activation or silencing of cancer-related genes and, consequently, the alteration of signaling pathways involved in the regulation of the cell cycle, differentiation, metabolism, cell growth and proliferation, and DNA repair mechanisms [7,8,9,10,11]

Elmastas et al

Moreover, the relationship between glial cell modulation and the molecular mechanisms underlying RGC death is multifaceted

In plants, there are two key enzymes involved in AsA recycling known as dehydroascorbate reductase (DHAR) and monodehydroascorbate reductase (MDHAR)

Lancet 389(10088):24922502