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10.1038/nrn916 Nat

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In IBD (inflammatory bowel disease), small intestinal epithelial cells of Crohns disease patients with impaired GPx4 activity and in IBD, Crohns disease patients small intestinal epithelial cell GPx4 activity is impaired and LPO (lipid peroxidation) is obvious

38 Similarly, another study showed that 25[OH]D supplementation failed to improve hypertension clinically in patients by decreasing their blood pressure 39 or by decreasing their systemic inflammatory markers

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Lipid dysregulation can also impact neurotransmission