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The 200 to 500mcg figures widely used across clinic and community contexts are derived from animal extrapolation and accumulated self-experimentation, not controlled human trials

In summary, while the existing evidence points toward a beneficial role for GA in liver disease, the consistent positivity should be interpreted with caution, likely reflecting a combination of genuine therapeutic activity, methodological limitations, and publication bias

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But the National Institutes of Health recommends adults take no more than 350 mg of magnesium as a supplement every day