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TUNEL-positive cells and 4-HNE accumulation were observed within TLS in both sulfasalazine-treated and vehicle-treated mice, while cleaved caspase-3, an apoptosis marker, was not evident in either group (Figure 5C)

Side effects may still occur and vary by patient 4

Yeh SW, Hong CH, Shih MC, Tam KW, Huang YH, Kuan YC

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Ethics statement The animal study was reviewed and approved by Institutional Bioethics and Biosecurity Committee of the Instituto de Investigaciones Qumico-Biolgicas, Universidad Michoacana de San Nicols de Hidalgo

10.1002/dmr.5610050304 Diabetes Metab Rev