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Pathologists in Italy have validated the efficacy of the glutathione

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Further preclinical studies have demonstrated that acupuncture at Baihui (GV20), Yintang (EX-HN3), and other related acupoints significantly inhibits microglial polarization toward the pro-inflammatory M1 phenotype and reduces the expression of TNF- and IL-1 by suppressing the Toll-like receptor 4 (TLR4)/Myeloid differentiation primary response 88 (MyD88)/NF-B signaling cascade, thereby attenuating neuroinflammation (Jiang et al., 2024)

Its role in cell metabolism is particularly significant, as it acts as a coenzyme in the synthesis of nucleic acids and the metabolism of carbohydrates and fats

That was indicated by significantly reduced BAX expression in the EMPA group compared to the PTZ group