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An imbalanced oxidative status due to the production of ROS can be reduced by the presence of antioxidants such as PtNPs [86]

Injectable glutathione is approved by FDA Philippines as an adjunct treatment in cisplatin chemotherapy

Invest 131 (12), e140723

demonstrated that Nos2-derived NO modulated the pathogenic IL-1 secretion from the local macrophages, which acted to downstream target innate lymphoid cell 3 (ILC3), resulting in the up-regulation of IL-17 A to trigger and accelerate the development of MIP [67]