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doi: 10.1016/j.lwt.2017.12.028 12 GaoY.LiuY.SunM.ZhangH.TuoY

Magalhaes PV, Dean OM, Bush AI, Copolov DL, Malhi GS, Kohlmann K, et al

Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity

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Excessive ROS not only directly oxidatively damage mtDNA, leading to mutations and deletions, but also induce mitochondrial membrane lipid peroxidation and protein functional inactivation, triggering decreased mitochondrial membrane potential and cytochrome C release (Zhen et al., 2023