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Description

Topiramate-associated renal tubular acidosis

A decrease in serine indicates the satisfaction of glycine requirements, which is mainly biosynthesized from serine and components of GSH

No adverse reactions were reported across the study

The finished peptide is presented as a white lyophilized (freeze-dried) powder

So far, there have been no known analytical techniques that can simultaneously determine APAP, NAPQI, and NAC as an antidote

Individual variation exists, but the pattern, rough month 2, improvement month 3, minimal symptoms months 4+, holds for about 85% of patients who complete treatment