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On the other hand, neutrophilic asthma, associated with lung infections, air pollution and obesity, is driven by a Th1/Th17 immune response ( For most asthma patients, symptoms can be effectively controlled by inhaled treatment with corticosteroids in combination with long-acting beta agonists, whilst long-acting muscarinic antagonists and leukotriene inhibitors maybe added for the treatment of poorly-controlled patients ( 1.3 Severe eosinophilic asthma Patients with severe eosinophilic asthma show a type 2 inflammatory response, severe airflow obstruction and frequent exacerbations, and are dependent on oral corticosteroids