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Good candidates generally have stable health status, understand the experimental nature of the therapy, and commit to appropriate monitoring protocols

Kasielski M, Nowak D (2001) Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease

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These changes can lead to dysregulation of gene expression and disruption of normal cellular processes

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Aflatoxin B1 Metabolism: Regulation by Phase I and II Metabolizing Enzymes and Chemoprotective Agents. Mutation Research