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Cell 118 , 757766 (2004)

doi: 10.1079/bjn19770049

In cholangiocarcinoma, combined BET degradation and mTOR inhibition synergistically reduce acetylation of PSAT1-associated H3K27, inducing PSAT1 downregulation and subsequent dysfunction of the serine-glycine-one-carbon (SGOC) pathway (114)

In MPTP-induced mice, EGCG not only activates PI3K/Akt survival signaling but also inhibits the MAPK pathway to reduce neuroinflammation and neuronal apoptosis (54)

16 Furthermore, NAPQI binds to complexes I and II, disrupting the electron transport chain and allowing electrons to escape and produce superoxide radicals

Hot cht ny can thip vo qu trnh chuyn ho, ngn nga hot ng ca enzyme tyrosinase, o ngc tin trnh tng hp sc t melanin sng mu thay v tng hp sc t melanin ti mu