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The peptide was observed to accelerate healing through multiple mechanisms: Faster granulation tissue formation in rat models Accelerated re-epithelialization at wound sites Enhanced dermal remodeling with organized collagen deposition Upregulated expression of c-Fos, c-Jun, and Egr-1 Growth Hormone Receptor Expression Research from Molecules revealed that BPC-157 upregulates growth hormone receptor expression in tendon fibroblasts

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doi: 10.1016/j.cell.2016.05.041 76 KoliadaA.SyzenkoG.MoseikoV.BudovskaL.PuchkovK.PerederiyV.et al

Acknowledgments We acknowledge the traditional custodians of the lands this project was conducted on, the Wurundjeri people of the Kulin nation, Professor Freya Fowkes (Burnet Institute) for assisting with statistical analysis, Dr Philippe Boeuf (Burnet Institute) and Professor Christian Doerig (RMIT) for helpful discussions and feedback on the manuscript, Professor Patrick Humbert (La Trobe University) for providing access to flow cytometry equipment, and The Australian Red Cross Blood Bank for the supply of human erythrocytes

Similar to glutamate, GABA is released in a Ca 2+ -dependent manner upon depolarization of the presynaptic membrane

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