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Membrane and Transmembrane Proteins Several membrane-bound proteins, particularly those on the cell surface, contain disulfide bonds that influence their folding and ligand-binding functions: Integrins : These adhesion molecules contain multiple disulfide bonds that regulate conformational states involved in cell-cell and cell-matrix interactions

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[DOI] [PubMed] [Google Scholar] 84.Alexanian I, Parissis J, Farmakis D, Athanaselis S, Pappas L, Gavrielatos G, Mihas C, Paraskevaidis I, Sideris A, Kremastinos D, et al

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At this point further modifications catalyzed by aldehyde dehydrogenase and aldo-keto reductase allow to obtain carboxyethylmercapturic acid and 3-hydroxypropylmercapturic acid respectively, which are escreted with urine (Fig

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Lipoic acid was found to upregulate the expression of -GCL and other antioxidant enzymes via the activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway (31, 33)

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