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Epub 2023 Mar 28

[Abstract]2024 Dec;56(1):2397572

4 Obesity is known to be strongly associated with type 2 diabetes

Additionally, models that rely on microbiomes may enhance the effectiveness of dietary treatments proposed to combat type 2 diabetes (168)

developed a novel DON prodrug, HDON, which can selectively activate nitroreductase in hypoxic tumor environments without affecting oxygen-rich normal tissues, showing significant tumor inhibition in the H22 mouse liver cancer model (Zheng et al., 2024)