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In contrast, we found that these metabolomic alterations led to a reduction in the plasma level of different metabolites including uridine, thymine, carnosine, theophylline, aspartate, taurine, serine, glutamate, tryptophan, arginine, and 53 other metabolites in the acute patients compared to HCs ( Supplementary Figures 6A, B )

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Such a twin study compares the similarity of a trait in mono-zygotic (MZ) and di-zygotic (DZ) twins [21, 22]

Int J Mol Med 44:19431951