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Contrary to X-ray crystallography or electron microscopy, NMR spectroscopy does not provide direct information on the 3D structures, i.e., spatial position of atoms, but rather indirect measurements such as local conformations (e.g., from chemical shifts) or atom proximities in space

10.3390/ijms22095010 [DOI] [PMC free article] [PubMed] [Google Scholar] Aquilano K., Baldelli S., Ciriolo M

Sigma-1 receptors may directly impact glutamatergic signaling by translocating to interact with NMDA receptors on the plasma membrane and modulating calcium influx (Fig

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Remember also that vitamin B12 and folic acid help synthesize neurotransmitters like dopamine and norepinephrine

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