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Recently, it was observed that VPA administration in Huh7 cells caused cell damage through the process of endoplasmic reticulum stresscaused due to the oxidation of glutathione (GSH) to glutathione disulfide (GSSG) as a consequence of GSH involvement in oxidative protein folding 15 and lipid peroxidation

These electrons can be taken up by a copper ion (Cu 2+ ) resulting in a copper atom (Cu) with no charge

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