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In addition, bortezomib treatment can also lead to mitochondrial damage, causing mitochondria to produce a large amount of reactive oxygen species (ROS), thereby damaging mitochondrial function and producing cytotoxic effects [29]

This undersells it

Quality Challenge #2: Absorption Barriers and Bioavailability Issues Research indicates that conventional NMN supplement formulations face degradation from stomach acid exposure, limiting how much actually reaches your cells

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