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Since H3K18la affects DNA transcriptional activity by enriching at the promoters of target genes, such as the oncogene c-Myc (20), this lactylation modification consequently confers therapy resistance by activating survival-related genes, including glutamate-cysteine ligase catalytic subunit (52)

2016 meta-analysis: Nine RCTs in 911 participants found carnitine supplementation resulted in 1.33 kg more weight loss than placebo [3][63]

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It suggested that introducing intra-luminal guidance channels has potential to encourage muscle regeneration [39]

Camargos CH, Yang L, Jackson JC, Tanganini IC, Francisco KR, Ceccato-Antonini SR, Camargos CHM, Rezende CA, Faria AF (2025) Lignin and nanolignin: next-generation sustainable materials for water treatment