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That is a meaningfully weaker claim than the titles phrasing implies, and it is the claim the evidence actually supports

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(B) Single-cell sequencing was used to analyze the expression level of NIK in each cell of the fibrotic kidneys

Ceramides also activate apoptosis by depleting the anti-apoptotic proteins like Bcl-2 in neurons (Jazvinak Jembrek et al., 2015), inhibits the Akt/PKB survival pathway and activates the mitogen-activated protein kinases (MAPKs) (Iwayama and Ueda, 2013)