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These finding are corroborated by Mummichog analysis, which showed substantial dysregulation of pathways involved in the metabolism of amino acids/secondary metabolites and glyoxylate/dicarboxylate in both the supernatant and cellular extract fractions (Fig

This has led to interest in NAC for conditions like systemic lupus erythematosus (SLE), where a small RCT found that NAC (2.4-4.8 g/day) improved disease activity scores and reduced anti-dsDNA antibody levels (Lai et al., Lupus, 2012) [42]

*Correspondence: Teresa G

Future research is expected to reveal increasingly complex and diverse interactions between lactylation and various PTMs networks

Eighteen compounds, accounting for 81.87%-98.87% of the total essential oil content, were identified in Salvia nemorosa (Table 3)

Other PTSD-relevant biological phenotypes include increase amygdala activity, suppression of hypothalamic pituitary adrenal axis activity and sleep impairments (Kamphuis et al., 2015