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Symptom reduction has also been observed in other chronic pain populations (71, 72)

& Matsuno-Yagi, A

J Allergy Clin Immunol 135(4):964971

Mortensen EM, Nakashima B, Cornell J, Copeland LA, Pugh MJ, Anzueto A et al

Furthermore, melatonin-stimulated exosomes derived from mesenchymal stem cells (MSCs) were found to enhance functional recovery in acute liver ischemia-reperfusion injury, suggesting that melatonin modifies the content of exosomes, which in turn modulates the microenvironment through paracrine mechanisms ( In the ischemic brain, oxidative stress and the generation of reactive oxygen species (ROS) can lead to oxidative damage in endoplasmic reticulum (ER) organelles, contributing to neuronal cell death after ischemia-reperfusion injury