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Description

AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

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Electrophysiological studies uncovered that GluN2A subunits mediate only 1030% of NMDA-evoked currents, whereas GluN2B subunits mediate over 70% of these currents in both human iPSC-derived neurons differentiated through an NPC stage and in NGN2 neurons [32, 112, 114], suggesting that GluN2B subunits dominate NMDAR responses in these neurons

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