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Hydrogen peroxide did not induce nucleus destruction without KCN, even at 1050 mM concentrations (Samuilov et al

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The validity of the approach was established by discovering that SDHB acquired its FeS clusters in stages, beginning with binding to HSC20 and ISCU, and progressing to ejection of the HSC20 transfer complex, transfer of the cluster to SDHB, binding of holo-SDHB to SDHA in the multiprotein SDHB complex, and finally to the membrane bound subunits, SDHC and SDHD (Maio et al

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