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" Yes, that's exactly my suspicion - that more frequent, lower doses could end up being more effective than the large doses that are standard at the moment

Given the vital role of Vit B12 in neural function, its deficiency may contribute to neurodegeneration and exacerbate motor and non-motor symptoms in PD patients

High doses of methylcobalamin have been used to treat multiple sclerosis (improved visual and auditory symptoms, not motor ones), amytropic lateral sclerosis, Parkinsons, and may help regenerate nerves and treat peripheral neuropathies

If this continues, dehydration spreads throughout the body

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Having too little (a deficiency) of a specific vitamin or mineral can lead to health problems