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Multiple strong studies showed that the traditional means of initiating a KD for inpatients, namely with a 2448 h fast, is not more effective, whilst being associated with an increased burden of adverse symptoms, particularly in the youngest children, when compared to gradual initiation techniques and starting on a full calorie KD (32, 64, 77)

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Studies on lumbar ESIs have revealed that they can provide reliable pain relief for up to 6 months in many cases