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Description

McCarty MF, DiNicolantonio JJ, OKeefe JH

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l'ester de 1,1-dimthylthyle d'acide [6-[[(4-bromo-2,6-dimthylphnyl)amino]carbonyl]-2-benzothiazolyl]carbamique

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In the cryo-EM structure, two suramin molecules bind to the active sites of nsp12, with one occupying the template-binding site and the other occupying the primer catalytic active centre, implying that suramin may competitively inhibit proteinRNA binding due to its strong electronegativity (Fig

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