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Journal of Pharmacy and Pharmacology, 69 (6), 625-632

Overall, Syn S129E exhibited promiscuous, nonfunctional interactions with a broad spectrum of proteins compared to the specific interactions observed for Syn WT

Numerous studies have shown that the apoptotic pathway is involved in the pathogenesis of these diseases, and it is activated only as a last resort when there is no possibility of neurons recovery ( Neurodegenerative diseases are characterized by the slow, progressive loss of neuronal cells in the central nervous system (CNS) and the aggregation of misfolded proteins (Singh et al., 2019)