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TB-500 has been examined in brain injury and neurodegeneration models with research documenting neuronal cell survival promotion through PI3K/Akt anti-apoptotic signalling, promotion of neurogenesis and oligodendrocyte progenitor migration following white matter injury, and anti-inflammatory effects in the injured CNS

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Targeting cGAS-STING signaling pathway Recent findings demonstrate that pharmacological agents, including CGRP and -sitosterol (SITO), exhibit protective effects against PH by modulating the cGAS-STING axis

Even after treatment with such conventional approaches, the patients may experience fluctuating symptoms, side effects from the medicines, and disease progression (14, 15)

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