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Effects of Vitamin injections or IV therapy are felt almost immediately

Additional support was provided by the Chung-Ang University Graduate Research Scholarship (Academic Scholarship for the College of Biotechnology and Natural Resources) in 2024

Data analysis is conducted using triangulation to ensure robustness

protein misfolding, mislocalization of TDP-43 to the cytoplasm, ER stress, inhibition of ER-Golgi transport, and apoptosis, in neuronal cells expressing pathological forms of TDP-43 or SOD1 (Parakh et al., 2020)

Furthermore, expression of WT, ALS-associated mutant, or truncated forms of TDP-43, promote CD14-mediated activation of microglia through NF-B signaling and NLRP3 inflammasomes (Zhao et al., 2015)