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To conclude, these data support the concept that synaptic activity-dependent induction of the intrinsic neuronal antioxidant defenses can act in concert with support provided by nearby astrocytes

A phase III study comparing the efficacy and safety of DFMO in combination with lomustine versus lomustine alone in patients with recurrent/progressive anaplastic astrocytoma following radiotherapy and temozolomide chemotherapy is also underway (NCT02796261)

The ultimate goal is to improve treatment effectiveness and overcome resistance mechanisms in T-cell cancers

10.3389/fphar.2024.1430469 24 DalgaardF.BondonnoN

Importantly, it also is the precursor of -aminobutyric acid, the ubiquitous inhibitory neurotransmitter in the brain

This product is a great option when the primary focus is support of movement, comfort, and cartilage