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SKU: 75297863143
Price: 28.19 USD
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This Review presents the evidence for autoinflammation and the evidence for autoimmunity in AS and, by discussing the pathophysiological factors associated with each, aims to reconcile the two hypotheses

MANF depends on CK19 and Notch2 to promote hepatocytes-derived ICC To investigate whether NICD2 alone plays a key role in the transdifferentiation of hepatocytes into ICC cells regulated by MANF, we applied AAVs (AAV8-TBG-shVector/Notch2) to downregulate Notch2 in hepatocytes in tdTomato MANF KI mice (Supplementary Fig