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and (iii) excellent metal chelating ability (Scheme 1)

During embryo development, MT1 is expressed and distributed inside the blastomere, and its expression levels are low in degenerated embryos

Moreover, supplementation with L

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Although ERT offers mutation-independent metabolic control, injectable agents such as pegtibatinase face lifetime adherence and immunogenicity hurdles, and oral agents such as SYNT-202 still require durable efficacy and safety data